Department

Pancreatic Transplantation Centre

What is Pancreas Transplant?

Pancreatic transplantation is a surgical procedure in which a healthy donor pancreas, usually from a brain dead donor, is implanted into a patient whose pancreas fails. This is usually a type I diabetic patient (as well as highly selected type 2 diabetics) whose pancreas fails to produce the required insulin. This is a specialized procedure and is performed by a pancreatic transplant surgeon.

Once the pancreas is removed from the donor it is kept viable by cooling it and preserving in ice cold preservative solution. It can be preserved only for a few hours after it is removed from the donor. In addition, the donor’s blood type must be compatible with the patient receiving the organ so that the body has a better chance of accepting the organ.

During a pancreatic transplant, the native pancreas is not removed during the operation. This is because it is still capable of making the essential digestive enzymes needed during the digestion of food. Instead, the donor pancreas is placed below the diseased pancreas and is attached to the patient’s blood vessels.


What are the types of Pancreatic Transplants?

There are three types of pancreatic transplant options:

  • Combined Pancreas Kidney Transplant or Simultaneous Pancreas Kidney (SPK) Transplant: As stated earlier, sometimes a kidney transplant is required for those suffering from type I diabetes as well as renal failure. Often, the pancreas and kidney will come from the same donor and be transplanted at the same time.
  • Pancreas after Kidney (PAK) Transplant: .In this case, kidney transplantation is done first, either from a living donor or a deceased (cadaver) donor. Pancreas transplantation is done after some time in a kidney recipient with a functioning kidney graft.
  • Pancreas Transplant Alone (PTA): Pancreas transplants that do not require kidney transplants are for those who have severe type I diabetes (episodes of hypoglycemia. hypoglycemic unawareness, ketoacidosis) but are not having kidney failure. This procedure is also done in patients who undergo total pancreatectomy.

 

What are the advantages of a Pancreatic Transplants?

There is much to be gained from receiving a healthy pancreas, especially if you are suffering from extreme renal disease:

  • With a healthy pancreas, you may no longer require insulin injections that result from your type I diabetes.
  • Many of your type I diabetes symptoms may lessen or go away altogether with the presence of a healthy pancreas that is functioning as it was meant to.
  • A healthy pancreas will prevent further damage to your already unhealthy kidneys or work well with the new kidney you receive, should you require a kidney transplant as well. Other complications of severe diabetes (end organ damage) such as neuropathy (damage to the nervous system), retinopathy (damage to the eye), vasculopathy are improved or the progression arrested following successful pancreas transplantation.

 

What are the risks of a Pancreatic Transplants?

Here is a look at some of the possible risks and/or complications that may result from a pancreas transplant:

  • Your body may reject the new organ as a foreign object, attack it, and render it useless.
  • You will have to take immunosuppressant drugs for the rest of your life to help prevent your body from rejecting the new organ. These drugs can lower your immune system and trigger bacterial and viral infections, and increase the chances of some cancers. However, if you are, also, having renal transplant you would be taking immunosuppressant medications anyhow.
  • Since 75% of all pancreas transplants are performed with kidney transplants, complications post-surgery are higher with higher rates of rejection of the new organs.

Pancreatic transplantation is a surgical operation that involves implanting a healthy donor pancreas, usually from a brain-dead donor, into a patient whose pancreatic has failed. This is typically a type I diabetic (as well as a subset of type 2 diabetics) whose pancreas fails to produce the necessary insulin. A pancreas transplant surgeon performs this complex treatment.


The pancreas is kept viable after being extracted from the donor by chilling it and keeping it in an ice-cold preservation solution. It can only be kept for a few hours after being withdrawn from the donor. You must contact the doctor about the Best Pancreas Transplantation Hospital in Kondapur and the Top Pancreatitis Hospitals in Kondapur.


But before knowing about the Pancreatitis Treatment Hospital In Kondapur and Best Transplantation Hospital in Kondapur some other essential things to know about. Furthermore, the donor's blood type must be compatible with the patient receiving the organ so that the body can accept the organ.


The original pancreas is not removed during pancreatic transplant surgery. This is due to the fact that it can still produce the key digestive enzymes required during food digestion. Instead, the donor pancreas is linked to the patient's blood arteries and put beneath the damaged pancreatic.


Pancreatic Transplantation Details

The Best Pancreas Transplantation Hospital in Kondapur and the Top Pancreatitis Hospitals in Kondapur vary from place to place. So before getting the treatment, you must know the Pancreatitis Treatment Hospital In Kondapur and Best Transplantation Hospital in Kondapur. Pancreatic transplants are classified into three types:

Combined Pancreas Kidney Transplant or Simultaneous Pancreas Kidney (SPK) Transplant: As previously indicated, patients with type I diabetes and renal failure may require a kidney transplant. Often, the pancreas and kidney come from the same donor and are transplanted together.


Pancreas after Kidney Transplant (PAK):

In this situation, either a living or deceased (cadaver) donor's kidney is transplanted first. After some time, a pancreas transplant is performed in a kidney recipient with a working kidney graft.


Pancreas Transplant Alone (PTA): Pancreas transplants without kidney transplants are for people with severe type I diabetes (hypoglycemia, hypoglycemic unawareness, ketoacidosis) but with no renal failure. This operation is also performed on patients who have had a total pancreatectomy.


To get the best treatment you must be aware of the Best Pancreas Transplantation Hospital in Kondapur and the Top Pancreatitis Hospitals in Kondapur. After knowing the Pancreatitis Treatment Hospital In Kondapur and Best Transplantation Hospital in Kondapur. Here are some of the potential dangers and/or consequences associated with a pancreatic transplant:

1. Your body may recognize the new organ as a foreign object and assault it, rendering it inoperable.

2. To prevent your body from rejecting the new organ, you will need to take immunosuppressive medicines for the rest of your life. These medications can suppress your immune system, cause bacterial and viral infections, and increase your risk of developing some cancers. However, if you are also undergoing a renal transplant, you will be receiving immunosuppressive drugs.

3. Because kidney transplants are used in 75% of pancreatic transplants, problems after surgery are more common, as are rates of rejection of the new organs.


FAQs


1. What is the rate of success for pancreas transplantation?

Pancreas transplantation is successful in approximately 90% of individuals who no longer require insulin shots during the first year of surgery.


2. Is a pancreas transplant common?

Pancreas transplants are among the most uncommon forms of organ transplants performed each year.


3. Who is a candidate for a pancreas transplant?

Candidates for pancreas transplantation typically have type 1 diabetes, combined with kidney dysfunction, nerve damage, vision issues, or another disease consequence. Typically, healthcare practitioners consider a transplant for someone whose diabetes has progressed despite medical treatment.

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